초록 |
Recently, various nano-scale materials including silver and copper nanoparticles have been actively studied for their capacity to effectively prevent bacterial growth. A critical challenge is to enhance the antibacterial properties of nanomaterials while maintaining their biocompatibility. The conjugation of multiple nanomaterials with different dimensions – such as spherical nanoparticles and high aspect-ratio nanotubes – may increase the target-specific antibacterial capacity of the consequent nanostructure while retaining an optimal biocompatibility. In this study, multi-walled carbon nanotubes are treated with a mixture of acids and decorated with silver and copper nanoparticles at a same time. The synthesized Ag/Cu-MWCNTs complexes are characterized by TEM, XRD, and EDS. The antibacterial function of Ag/Cu-MWCNTs are evaluated against Methylobacterium spp. and Sphingomonas spp. In addition, the biocompatibility of Ag/Cu-MWCNTs are evaluated using both AML 12 and PBMCs. |