| 학회 |
한국고분자학회 |
| 학술대회 |
2015년 봄 (04/08 ~ 04/10, 대전컨벤션센터) |
| 권호 |
40권 1호 |
| 발표분야 |
의료용 고분자 부문위원회 II |
| 제목 |
Properties and Osteogenic Differentiation of BMSC on Demineralized Bone Particle Coated Silk Fibroin Scaffold |
| 초록 |
Silk fibroin and demineralized bone particle (DBP) scaffolds were fabricated by EDC cross linking for seeding bone marrow mesenchymal stem cell. Cell proliferation activity was measured via MTT assay. Osteogenic differentiation had been activated better with Silk/DBP scaffolds than silk fibroin scafffolds at all time points. Morphological observation, histology, biological assay for collagen type I, osteocalcin and runx-2. SEM results showed that silk fibroin scaffolds with DBP have smaller pores than without it. This study showed that DBP helps osteogenic differentiation of BMSC on silk fibroin scaffolds. This research was supported by the Brain Korea 21 PLUS Project, NRF, Bio-industry Technology Development Program(KMFAFF, 112007-05-2-SB010). |
| 저자 |
이선의1, 국현1, 김수민1, 김은영1, 박찬흠2, 강길선1
|
| 소속 |
1전북대, 2한림대 |
| 키워드 |
Bone marrow mesenchymal stem cell; Demineralized bone particle(DBP); Osteogenic differentiation
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| E-Mail |
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