| 초록 |
Electrospinning is a novel technique in the fabrication of fine fibers from polymeric liquids. Electrospun nanofiber mats have advantageous properties to biomedical uses such as high surface area to volume ratio and high porosity. Among the synthetic biodegradable and electrospinable polymers, aliphatic polyester family has widely been used in biomedical devices, which include polyglycolide (PGA), poly(ε-caprolactone) (PCL) and poly lactic acid (PLA). These nanofiber surfaces need to be modified to well interact with cells or mimic the natural extracellular matrix (ECM). Among several methods for modifying surface properties, gas plasma reactions have usefully been used to modulate hydrophilicity and improve cell adhesion and viability. In this work, we modified electrospun PCL nanofiber by oxygen plasma treatment and assessed its biocompatibility to astrocyte cells. . |
