초록 |
Wrinkled hydrogel films have a high potential value in a wide range of applications including sensors, responsive coatings and adhesives. In this study, we develop a method to reversibly fabricate the desired shape of wrinkles. We irradiate the monomer solution with diffused UV lamp light via a pinhole array photomask(< 10 µm). As a result, a hydrogel film with a rugged surface can be obtained. Hydrogel film made of pH-responsive material, poly(2-hydroxyl methacrylate-co-acrylic acid) (p(HEMA-co-AA)) is swell depending on pH. Subsequently, a wrinkled structure is formed on the surface of the hydrogel film reversibly in accordance pH. It is possible to obtain wrinkles of various patterns such as a square or a hexagon in keeping with the photomask pattern. Eventually, we observe that Escherichia coli on wrinkled hydrogel film are grown followed by wrinkle patterns which can be used for positioning individual cells for bioapplications. |