화학공학소재연구정보센터
학회 한국화학공학회
학술대회 2016년 봄 (04/27 ~ 04/29, 부산 BEXCO)
권호 22권 1호, p.238
발표분야 공정시스템
제목 Real time optimization of microalgae cultivating system
초록 Bio-oriented secondary metabolites production characterized by distinct cultivation environment of growth and production, is optimized in a framework of two-stage approach. Each stage's kinetic models are constructed by using logistic  and Luedeking-Piret model and utilized for searching the termination times having optimal productivity and time yield. In addition, the kinetic models are modified in real-time manner for compensating the plant model mismatch. Simulation results show that termination of both stages in transient condition has improved yield, being compared with the yield of steady state strategy. Based on these results, necessities of proper two-stage schedule optimization in real-time manner  for plant scale bio-process are raised.
This research was supported by Basic Science Research Program through the National Research Foundation of Korea(NRF) funded by the Ministry of  Science, ICT & Future Planning(2015R1A1A1A05001310)
저자 정동휘, 이종민
소속 서울대
키워드 공정모델링; 공정최적화; 공정제어
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