화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2014년 가을 (10/06 ~ 10/08, 제주 ICC)
권호 39권 2호
발표분야 X-ray & Neutron Scattering for Polymer Science
제목 Transformation of Protein Tubule by Molecularly Triggered Conformation Switch
초록 Microtubule(MT) is a hollow cylindrical biopolymer comprised of assembled αβ-tubulin heterodimers. They are involved in a variety of cellular functions, including cell division, intracellular transport, and cell morphology. Using small angle X-ray/Neutron scattering and transmission electron microscopy, we quantitatively examined the nature of BMTs-to-BITT†, MTs-to-SMTs, DWMTs, and BDWMTs transformation pathways, which results from cationic molecule triggered conformation switch. †Nature Materials 13 195 (2014) MT bundles (BMTs), Inverted tubulin tubule (BITT), MT sheets (SMTS), Double-walled-MTs (DWMTs), DWMT bundles (BDWMTs)
저자 최명철
소속 KAIST
키워드 biopolymer; microtubule (MT); small angle X-ray/Neutron scattering; transmission electron microscopy
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