| 초록 |
Influenza A, one of the contagious diseases, is predominantly transmitted through aerosol, which led to development of filters and masks. Among them, high-efficiency particulate air (HEPA) filters which can filtrate 0.3μm particulates with efficiency of 99.97% is in a big interest but they are still not absolute filters. Tannic acid (TA) has antiviral effects and ability to induce interactions with various materials. Even there are many reports demonstrating introduction of antiviral agents to filters, they are often too complicated and expensive. In this work, we demonstrate stable and easy-made TA-HEPA filters which are capable of effective capture of influenza virus. Its capability was confirmed by SEM analysis and in-solution tittering methods including neuraminidase activity assay and plaque reduction assay. Thus, our results suggest TA-HEPA filters is potent anti-influenza filters and have potential in devices for preventing broad-spectrum pathogenic viruses. |
