| 초록 |
In this study, the integrated cell-based bio-actuator was fabricated using a DLP 3D printer and subsequently filling the cell-matrix composed of collagen, Matrigel, biomaterials and live skeletal muscle cells. Also, geometric design was optimized for stress-induced 3D alignment of differentiated skeletal muscle cells. Next, electrical stimulation triggered contraction of engineered skeletal muscle cells and movement of the integrated cell-based actuator. Specifically, this cell-based bio-actuator system was able to be developed as an integrated cellular machine for a broad array of Bio-Micro-Electro-Mechanical Systems by a modular assembly such as series or parallel connection of living bio-actuator for enhancing contractile power. |
