| 학회 |
한국고분자학회 |
| 학술대회 |
2009년 가을 (10/08 ~ 10/09, 광주과학기술원 오룡관) |
| 권호 |
34권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 |
| 제목 |
Unusual trend of reverse thermal gelling poly(ethylene glycol)-DL-poly(alanine) diblock copolymers |
| 초록 |
The poly(ethylene glycol)-block-poly(DL-alanine) (mPEG-PA) diblock copolymers underwent an unusual sol-to-gel transition as the temperature increased. As the block length of the hydrophobic polypeptide increased the sol-to-gel transition temperature did not simply change. The cryo-TEM image showed vesicle-micelle-fibrous shape at low concentration as the PA block length increased. Peptides kept their random coil conformation whereas PEG was dehydrated as the temperature increased. The abnormality seems to be caused by the difference in aggregation patterns of the polymer in water. |
| 저자 |
주민경, 박수현, 정병문
|
| 소속 |
이화여자대 |
| 키워드 |
thermosensitive; sol-gel transition; polypeptide
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| E-Mail |
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