| 초록 |
Alginate has biocompatibility, biodegradation, and it has high resistance to antibiotics and kills macrophages. Alginate was modified furfuryl group, and the furfuryl alginate (F-alginate) was mixed riboflavin for visible light reactivity. Riboflavin was shown no cytotoxicity in vitro test. The introduction of furfuryl group was identified by 1H-NMR and UV/vis spectroscopy. To apply in anti-adhesion field, cytotoxicity test, anti-bacterial activity, and animal test were performed. In conclusion, it was demonstrated that the system prevented tendon adhesion. |
