화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2019년 가을 (10/30 ~ 11/01, 제주국제컨벤션센터(ICC JEJU))
권호 23권 2호
발표분야 포스터_생체재료
제목 3D Printed Poly lactic acid Scaffolds containing Dipyridamole, Mimicking Tetrapod structure.
초록 We produced a poly lactic acid (PLA) filament containing dipyridamole (DIP), and then printing a scaffold with tetrapod-interlocking structure through a fused deposition modeling (FDM) printer. The Tetrapod-interlocking structure was designed through CAD and converted to G-code using the slic3r slicing program. Mechanical properties of the prepared scaffolds were measured via universal testing machine. The tetrapod and cubic structures showed similar compressive stress endurance. Tetrapod and cubic structures showed similar compression stress endurance, but tetrapod scapold showed more flexibility. The interlocked structure showed better stress resistance and flexibility than tetrapod scaffold, preventing sudden breakage and providing more compressive endurance. PLA scaffolds consistently released DIP over time and had a positive effect on osteoblast proliferation. Overall, we believe that DIP / PLA tetrapod-interlocked scaffolds can be used for bone tissue engineering.
저자 최인성, 최성욱
소속 가톨릭대
키워드 Poly Lactic acid; dipyridamole; Tetrapod sturcture; 3D printing
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