화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2013년 봄 (04/11 ~ 04/12, 대전컨벤션센터)
권호 38권 1호
발표분야 기능성 고분자
제목 Preparation and characterization of pH-sensitive sodium alginate/poly(vinyl alcohol)/bentonite blend beads for controlled release of diclofenac sodium
초록 In order to enhance the drug entrapment efficiency and improve the swelling behaviors of drug delivery system, Ca2+ crosslinking technique was used to prepare sodium alginate/ poly(vinyl alcohol)/betonite beads. Beads of different compositions were prepared by varying the amount of poly(vinyl alcohol) and bentonite and characterizing it by Fourier transform infrared spectroscopy (FTIR), X-ray diffraction(XRD). The swelling and pH-sensitive properties of the beads were investigated, and the drug loading and controlled release properties of the beads were also evaluated using diclofenac sodium as the model drug.
저자 정경희, 강세미, 이재호, 황대연, 정영진
소속 부산대
키워드 Alginate; Poly(vinyl alcohol); Bentonite; Controlled release
E-Mail hlb@pusan.ac.kr