| 학회 | 한국고분자학회 |
| 학술대회 | 2004년 가을 (10/08 ~ 10/09, 경북대학교) |
| 권호 | 29권 2호, p.175 |
| 발표분야 | 고분자 합성 |
| 제목 | Synthesis of Functional Aliphatic Polyesters Derived from Galactaric Acid |
| 초록 | Synthetic aliphatic polyesters that can be bioassimilated are increasingly investigated worldwide for pharmacological, biomedical, and environmental purposes due to their biodegradability, bioabsorbability and biocompatibility. These can be prepared from a large variety of compounds according to various synthetic routes. Judicious choice of the repetitive ester units allows to modulate the physico-chemical properties. Particularly, multifunctional polyesters containing many hydroxyl groups as the pendant groups are of great interest in this respect. These polymers are highly desirable for tailoring properties including hydrophilicity, permeability, biodegradation rate, bioadhesion, and biological activity. Furthermore, these pendant groups are able to promote H-bonding interactions and the control of the degree of H-bonding is a well established and effective method for modulating the material characteristics, such as crystallinity, glass transition temperature, toughness, stiffness, etc. It has been reported that polyhydroxypolyesters have been generally synthesized via a complicated protecting-deprotecting reaction pathway from which several problems can arise. In this study, we tried to synthesize polyhydroxypolyesters using between galactaric acid and diol without a complicated protecting-deprotecting reaction pathway. The polyesters were prepared by two methods, which are two stage reaction method using chemical catalysts and biocatalytic synthesis using enzyme. We investigated in detail the reaction condition for the simple polycondensation including reaction times, temperature, and catalysts. Polymerization behavior was monitored as functions of conversion, molecular weight change, catalytic effects, etc, using various techniques such as FTIR, 1H-NMR, GPC, etc. |
| 저자 | 차주은, 박종래 |
| 소속 | 서울대 |
| 키워드 | polyhydroxypolyester; high molecular weight; chemical catalyst; enzyme |
