초록 |
In this study, we present a simple aqueous solution-based strategy to construct an effective photothermal nanocomposite composed of poly (3,4-ethylenedioxythiophene) poly(styrene-sulfonate) (PEDOT:PSS) and agarose with thermo-processability, light triggered self-healing, and excellent antibacterial activity. The PEDOT:PSS/agarose all-organic nanocomposite hydrogel exhibited a sharp temperature increase of 24.5 °C during NIR exposure for 100 sec. More importantly, we demonstrated that the temperature increase on PEDOT:PSS/agarose via photothermal conversion resulted in the rapid and effective killing of nearly 100 % of the pathogenic bacteria within 2 min of NIR irradiation, as well as possessing thermoplasticity and NIR light-assisted self-healing properties. We envision that smart conducting nanocomposite hydrogel with unique properties may find broad utility in future bioapplications, especially in photothermal therapy, biomimetic devices, and smart bioelectrodes. |