| 학회 |
한국공업화학회 |
| 학술대회 |
2014년 가을 (11/12 ~ 11/14, 엑스코(대구)) |
| 권호 |
18권 2호 |
| 발표분야 |
생물공학-포스터 |
| 제목 |
Evaluation to stability of Liposomes |
| 초록 |
Liposomes which are made of phospholipids and cholesterolsare similar to biological membranes. Liposomes have been applied in transdermaldelivery system (TDS) due to their significant biocompatibility. In this study,we synthesize nano-liposomes to improve the function of permeation to keratin.We investigate the shape of liposomes following to synthesizing variable ratio withegg phosphatidylcholine and cholesterol. In addition, we compare the stabilityof liposomes depend on using lyoprotective materials like sucrose and maltose.As a result, we can increase the chemical and physical stability of liposomesin dispersion state. We analyzed the characteristic of liposomes throughmicroscope as well as calculate the zeta potential. Furthermore, we study thestability of liposomes through analyzing one that are stored during 5 and 10days. Nano-liposomes can be applied to anti-aging and wound healing process asthey make the fibroblasts create a large amount of collagen. |
| 저자 |
현성진, 강민지, 윤선주, 김재혁, 정아연, 지승배, 이우걸
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| 소속 |
단국대 |
| 키워드 |
liposome; stability; TDS; phospholipids
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| E-Mail |
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