| 학회 | 한국공업화학회 |
| 학술대회 | 2020년 가을 (10/28 ~ 10/30, 광주 김대중컨벤션센터(Kimdaejung Convention Center)) |
| 권호 | 24권 1호 |
| 발표분야 | [생체재료] 미래기술을 위한 바이오 소재 혁신 |
| 제목 | Biomaterials Strategies for Therapeutic Applications |
| 초록 | Great progress in medical diagnostics, tissue engineering, drug delivery and implants can be attributed to the advances in biomaterials. In our lab, we have developed a novel enzymatic method for facile immobilization of bioactive molecules, (antifouling polymers, antibacterial and nitric oxide-generating compounds) onto the surfaces. This approach using Tyrosinase (Tyr)-catalyzed oxidative reaction to convert phenol molecules into o-quinones and form reversible coordination bonds to metallic substrates or polymeric substrates. The method takes advantage of fast reactions under very mild conditions. In addition, peroxidase based in-situ forming hydrogels will be discussed in the presentation. In summary, these rapid enzymatic reactions are effective for surface immobilization of bioactive molecules and in-situ forming hydrogels to improve the in vivo performance of biomaterials Acknowledgement: NRF-2018R1A2B2004529 & 2019R1A6A1A11051471 |
| 저자 | 박기동 |
| 소속 | 아주대 |
| 키워드 | Biomaterials; Surface modification; In situ forming hydrogels |
