화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2008년 봄 (05/09 ~ 05/10, 한양대학교(안산))
권호 12권 1호
발표분야 생물공학
제목 Effect of L-ascorbic acid immobilized within calcium phosphate on the marker gene expression of osteoblastic MG63 cell
초록 Ascorbic acid has been extensively studied as an essential role in the synthesis and function of skeletal tissue. Ascorbic acid, also known as vitmin C, is a major physiological antioxidant, reparing oxidatively damaged biomolecules. Our study demonstrate that ascorbic acid-functionalized calcium phosphate prepared at a multiplicity of concentrations can watch the development of the osteogenic differentiation. The expression levels of marker gene such as osteocalcin, osteopontin, osteonectin, and alkaline phosphatase, TGF-β, and typeⅠ-collagen, has been analyzed using reverse transcriptase polymerase chain reaction (RT-PCR).
저자 양원규, 이우걸
소속 단국대
키워드 ascorbic acid; calcuim phosphate; RT-PCR
E-Mail