화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2017년 봄 (05/10 ~ 05/12, 광주 김대중컨벤센센터(Kimdaejung Convention Center))
권호 21권 1호
발표분야 생체재료
제목 Enhancement of the biofunctionality of collagen-chitosan hydrogel.
초록 In this study, we incorporated chitosan to collagen matrix to improve its properties for cell proliferation and differentiation. Different ratios of collagen and chitosan were mixed and chemically-crosslinked to produce hydrogels. Swell and degradation assays showed that chitosan improved the stability of the collagen hydrogel. In culture, murine fibroblasts formed significantly more proliferation-like structures on collagen–chitosan than chitosan-only matrix. The morphological structure of the hydrogel was analyzed using SEM. The chemical state was evaluated using Fourier transform infrared and energy dispersive spectrometer. In vitro assessments on fibroblast adhesion and proliferation were performed.
저자 성정희, 공영진, 김수정, 유혜진, 함정선, 이우걸
소속 단국대
키워드 collagen; chitosan; hydrogel; proliferation
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