| 학회 |
한국고분자학회 |
| 학술대회 |
2007년 가을 (10/11 ~ 10/12, 일산킨텍스) |
| 권호 |
32권 2호 |
| 발표분야 |
의료용 고분자 |
| 제목 |
Characterization of synthetic absorbable Polydioxanone monofilament suture |
| 초록 |
The purpose of this work was to characterize the physical and hydrolytic degradation properties of synthetic absorbable Polydioxanone monofilament suture, PDS* II. For the hydrolytic degradation study, we treated the specimen in a phosphate buffered Saline, pH 7.4 at 37℃ for 4months with shaking at a speed of 60times/min. We investigated the physical properties such as tensile strength, thermal transition properties, crystallization behavior, thermal decomposition properties, molecular weight, surface image and pH of the specimen using Tensile Tester, DSC, TGA, GPC, FE-SEM and pH meter as a function of hydrolysis time. The results showed that the synthetic absorbable Polydioxanone monofilament suture was degraded by two steps at different speeds and the breaking strength retention after 4weeks in vitro hydrolysis was about 85% of its initial strength. The molecular weight was decreased continuously and the speed of crystallization was increased with the hydrolysis time. |
| 저자 |
이준희1, 고석연1, 민범찬1, 곽철호2, 김선호3, 권수한4, 신재섭4, 김봉식5
|
| 소속 |
1(주)삼양사 중앙(연), 2(주)삼양사, 3(주)삼양 EMS, 4충북대, 5영남대 |
| 키워드 |
Absorbable Polydioxanone monofilament suture; PDS* II; Phosphate buffered Saline; In vitro hydrolysis; Breaking strength retention.
|
| E-Mail |
|
