초록 |
Nanoscale distance-dependent phenomena, such as Förster resonance energy transfer, are important interactions for use in sensing and imaging, but their versatility for bioimaging can be limited by undesirable photon interactions with the surrounding biological matrix, especially in in vivo systems. Here, we report a new type of magnetism-based nanoscale distance-dependent phenomenon, which is magnetic resonance tuning (MRET), that can quantitatively and reversibly sense and image intra-/intermolecular interactions of biologically important targets. With MRET, we demonstrate the successful detection of biological targets in in vivo systems. MRET can serve as a novel sensing principle to augment the exploration of a wide range of biological systems. |