화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2009년 봄 (04/09 ~ 04/10, 대전컨벤션센터)
권호 34권 1호
발표분야 고분자 가공/복합재료
제목 Biocompatibility of Water-Soluble Double-Layer Silane Encapsulated CdSe/ZnS Quantum Dots for Bio-Imaging
초록 Water-soluble double-layer silane (DLS) encapsulated CdSe/ZnS quantum dots (QDs) were prepared via encapsulation with silane coupling agent and evaluated the biocompatibility via cytotoxicity test and in vitro imaging. First, the QDs were encapsulated with alkoxysilanes via hydrophobic interaction and subjected to the second layer formation with 3-aminopropyltrimethoxysilane (-APS). The DLS encapsulated QDs were characterized by UV-Vis, PL and TEM. The biocompatibility of DLS encapsulated QDs was evaluated by measuring their cytotoxicity via MTT assay with HeLa cells. In addition, the in vitro images of DLS encapsulated QDs uptaken in HeLa cells were obtained by fluorescent confocal microscopy.
저자 백관열1, 윤태호2
소속 1광주과학기술원 / 바이오광학영상센터, 2광주과학기술원
키워드 Quantum Dot; Silane coating
E-Mail