화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2012년 봄 (04/12 ~ 04/13, 대전컨벤션센터)
권호 37권 1호
발표분야 의료용고분자 부문위원회
제목 Biodegradable cell-cross-linked hydrogels for tissue regeneration
초록 Hydrogels have been widely utilized in tissue engineering as they can be injected into the body in a minimal invasive manner. We developed biodegradable RGD-alginate/hyaluronate hydrogels in the presence of chondrocytes. Biodegradable RGD-alginate/hydrogels significantly enhanced cartilage formation 6 weeks post-injection into the dorsal of mice, in comparison with non-degradable gels, which was confirmed by analysis of GAG content and expression levels of chondrogenic marker genes. Biodegradable cell-cross-linked gels could find useful applications in many tissue engineering applications.
저자 박홍현, 이근용
소속 한양대
키워드 alginate; hyaluronate; RGD; tissue engineering
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