화학공학소재연구정보센터
검색결과 : 33건
No. Article
1 Identification of SARS-CoV-2 inhibitors using lung and colonic organoids
Han YL, Duan XH, Yang LL, Nilsson-Payant BE, Wang PF, Duan FY, Tang XM, Yaron TM, Zhang T, Uhl S, Bram Y, Richardson C, Zhu JJ, Zhao ZP, Redmond D, Houghton S, Nguyen DHT, Xu D, Wang X, Jessurun J, Borczuk A, Huang YX, Johnson JL, Liu YR, Xiang J, Wang H, Cantley LC, TenOever BR, Ho DVD, Pan FC, Evans T, Chen HJ, Schwartz RE, Chen SB
Nature, 589(7841), 270, 2021
2 Identification of SARS-CoV-2 inhibitors using lung and colonic organoids
Han YL, Duan XH, Yang LL, Nilsson-Payant BE, Wang PF, Duan FY, Tang XM, Yaron TM, Zhang T, Uhl S, Bram Y, Richardson C, Zhu JJ, Zhao ZP, Redmond D, Houghton S, Nguyen DHT, Xu D, Wang X, Jessurun J, Borczuk A, Huang YX, Johnson JL, Liu YR, Xiang J, Wang H, Cantley LC, TenOever BR, Ho DVD, Pan FC, Evans T, Chen HJ, Schwartz RE, Chen SB
Nature, 589(7841), 270, 2021
3 A covalent small molecule inhibitor of glutamate-oxaloacetate transaminase 1 impairs pancreatic cancer growth
Yoshida T, Yamasaki S, Kaneko O, Taoka N, Tomimoto Y, Namatame I, Yahata T, Kuromitsu S, Cantley LC, Lyssiotis CA
Biochemical and Biophysical Research Communications, 522(3), 633, 2020
4 Age-induced accumulation of methylmalonic acid promotes tumour progression
Gomes AP, Ilter D, Low V, Endress JE, Fernandez-Garcia J, Rosenzweig A, Schild T, Broekaert D, Ahmed A, Planque M, Elia I, Han J, Kinzig C, Mullarky E, Mutvei AP, Asara J, de Cabo R, Cantley LC, Dephoure N, Fendt SM, Blenis J
Nature, 585(7824), 283, 2020
5 Age-induced accumulation of methylmalonic acid promotes tumour progression
Gomes AP, Ilter D, Low V, Endress JE, Fernandez-Garcia J, Rosenzweig A, Schild T, Broekaert D, Ahmed A, Planque M, Elia I, Han J, Kinzig C, Mullarky E, Mutvei AP, Asara J, de Cabo R, Cantley LC, Dephoure N, Fendt SM, Blenis J
Nature, 585(7824), 283, 2020
6 A Chemoproteomic Strategy for Direct and Proteome-Wide Covalent Inhibitor Target-Site Identification
Browne CM, Jiang BS, Ficarro SB, Doctor ZM, Johnson JL, Card JD, Sivakumaren SC, Alexander WM, Yaron TM, Murphy CJ, Kwiatkowski NP, Zhang TH, Cantley LC, Gray NS, Marto JA
Journal of the American Chemical Society, 141(1), 191, 2019
7 High-fructose corn syrup enhances intestinal tumor growth in mice
Goncalves MD, Lu CY, Tutnauer J, Hartman TE, Hwang SK, Murphy CJ, Pauli C, Morris R, Taylor S, Bosch K, Yang SJ, Wang YM, Van Riper J, Lekaye HC, Roper J, Kim Y, Chen QY, Gross SS, Rhee KY, Cantley LC, Yun JY
Science, 363(6433), 1345, 2019
8 Double PIK3CA mutations in cis increase oncogenicity and sensitivity to PI3K alpha inhibitors
Vasan N, Razavi P, Johnson JL, Shao H, Shah H, Antoine A, Ladewig E, Gorelick A, Lin TY, Toska E, Xu GT, Kazmi A, Chang MT, Taylor BS, Dickler MN, Jhaveri K, Chandarlapaty S, Rabadan R, Reznik E, Smith ML, Sebra R, Schimmoller F, Wilson TR, Friedman LS, Cantley LC, Scaltriti M, Baselga J
Science, 366(6466), 714, 2019
9 Chromosomal instability drives metastasis through a cytosolic DNA response
Bakhoum SF, Ngo B, Laughney AM, Cavallo JA, Murphy CJ, Ly P, Shah P, Sriram RK, Watkins TBK, Taunk NK, Duran M, Pauli C, Shaw C, Chadalavada K, Rajasekhar VK, Genovese G, Venkatesan S, Birkbak NJ, McGranahan N, Lundquist M, LaPlant Q, Healey JH, Elemento O, Chung CH, Lee NY, Imielenski M, Nanjangud G, Pe'er D, Cleveland DW, Powell SN, Lammerding J, Swanton C, Cantley LC
Nature, 553(7689), 467, 2018
10 Suppression of insulin feedback enhances the efficacy of PI3K inhibitors (vol 560, pg 499, 2018)
Hopkins BD, Pauli C, Du X, Wang DG, Li X, Wu D, Amadiume SC, Goncalves MD, Hodakoski C, Lundquist MR, Bareja R, Ma Y, Harris EM, Sboner A, Beltran H, Rubin MA, Mukherjee S, Cantley LC
Nature, 563(7731), E24, 2018