The effect of the temperature on the Crystal Size Distribution (CSD) in antisolvent crystallization operation, for systems where the solubility is weakly dependent on the temperature, is analyzed. The hydrogen bonding properties of the solvents used that influence the supersaturation of the solution and consequently the growth and the nucleation dynamic can explain this effect on the CSD. To verify and quantify these effects, experiments were conducted and the Fokker-Planck modeling equations were used to obtain the quantifying parameters (growth velocity, the asymptotic mean size, and the diffusivity). Results are provided through investigations into the nonisothermal antisolvent crystallization of sodium chloride (NaCl), in which the solubility is practically independent of temperature for the range of operating conditions considered.