Solid-liquid equilibrium (SLE) measurements for disodium 4,4'-dinitrostilbene-2,2'-disulfonate (DNSNa) and sodium 4-nitrotoluene-2-sulfonate (NTSNa) in aqueous ethylene glycol monoethyl ether solution and aqueous ethylene glycol monobutyl ether solution were conducted using a dynamic method over the temperature range from (280 to 335) K. A synergistic effect on DNSNa solubility was observed with the maximum solubility at solute-free mass fraction of ethylene glycol monoethyl ether w(3)(0) = 0.4000 and solute-free mass fraction of ethylene glycol monobutyl ether w(4)(0) = 0.5999, respectively. The solubility data were correlated using the thermodynamic electrolyte non-random two-liquid (E-NRTL) model and model parameters were determined simultaneously. Aqueous ethylene glycol monobutyl ether solution at solute-free mass fraction of ethylene glycol monobutyl ether w(4)(0) = 0.2000 was found to be suitable solvent medium for the oxidation of 4-nitrotoluene-2-sulfonic acid (NTS) to 4,4'-dinitrostilbene-2,2'-disulfonic acid (DNS) and the conclusion was confirmed using the static analytical method combined with UV-VIS spectrophotometer. (C) 2013 Elsevier Ltd. All rights reserved.