The purpose of the present work is to investigate novel approaches, materials, and molecules for the abatement of carbon dioxide (CO2) at the pre-combustion stage of gasification-based power generation point sources. The capture/separation step for CO2 from large point sources is a critical one with respect to the technical feasibility and cost of the overall carbon sequestration scenario. For large point sources, such as those found in power generation, the carbon dioxide capture techniques being investigated by the office of Research and Development of the National Energy Technology Laboratory possess the potential for improved efficiency and reduced costs as compared to more conventional technologies. The investigated techniques can have wide applications, but the present research is focused on the capture/separation of carbon dioxide from fuel gas (pre-combustion gas) from processes such as the Integrated Gasification Combined Cycle (IGCC) process. For such applications, novel concepts are being developed in wet scrubbing with physical sorption, chemical sorption with solid sorbents, and separation by membranes. In one concept, a wet scrubbing technique is being investigated that uses a physical solvent process to remove CO2 from fuel gas of an IGCC system at elevated temperature and pressure. The need to define an "ideal" solvent has led to the study of the solubility and mass transfer properties of various solvents. Pertaining to another separation technology, fabrication techniques and mechanistic studies for membranes separating CO2 from the fuel gas produced by coal gasification are also being performed. Membranes that consist of CO2-philic ionic liquids encapsulated into a polymeric substrate have been investigated for permeability and selectivity. Finally, processes based on dry, regenerable sorbents are additional techniques for CO2 capture from fuel gas. An overview of these novel techniques is presented along with a research progress status of technologies related to membranes and physical solvents. (C) 2008 Elsevier B.V. All rights reserved.