| 학회 |
한국공업화학회 |
| 학술대회 |
2011년 봄 (05/11 ~ 05/13, 제주국제컨벤션센터) |
| 권호 |
15권 1호 |
| 발표분야 |
정밀화학 |
| 제목 |
In vitro Test of Folic Acid-PEG-LMWSC-MTX |
| 초록 |
We prepared Folic Acid-PEG-LMWSC-Methotrexate (FALMMTX) using LMWSC-Methotrexate (LMMTX) and Folic Acid (FA). FA-PEG-LMWSC-Methotrexate(MTX) was synthesized by chemical reaction with Folic Acid-PEG-LMWSC and MTX. Chemical structure were investigated by FT-IR, NMR. Particle size was measured with DLS, shape and morphology were observed by TEM. And we carried out cytotoxicity and anticancer activate experiment. This polymeric material is expected for therapeutic targeted drug delivery system. |
| 저자 |
손동희, 남정표, 박준규, 김원석, 최창용, 장미경, 나재운
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| 소속 |
순천대 |
| 키워드 |
LMWSC; PEG; Folic Acid; Methotrexate; Cancer therapy.
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| E-Mail |
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