| 학회 |
한국공업화학회 |
| 학술대회 |
2011년 가을 (11/02 ~ 11/04, 경원대학교) |
| 권호 |
15권 2호 |
| 발표분야 |
정밀화학 |
| 제목 |
Preparation and Applicaiton of Carboxymethyl Chitosan andQuinolone antibacterial agents by Chemical reation |
| 초록 |
N-Carboxymethyl chitosan(NCMchitosan) was prepared by chemical reaction withglyoxylic acid to low molecular weight water soluble chitosan(LMWSC) of C2-NH2 (N-Carboxymethylc chitosan) group to apply as protein and drug carrier. Chitosan-antibacteral agents was prepared by chemical reaction with Chitosan and antibacteral agents for application possibility of drug delivery system. The structual characterisitcs of NCMCh-Quinolone antibacterial agents was investigated by FT-IR, 1H NMR. The release behaviors of Chitosan-antibacteral agents from this proposed delivery system in phosphate-buffered saline (PBS) solution at 37 °C were studied by fluorescence spectroscopy. |
| 저자 |
홍락준, 남정표, 김영민, 이경재, 박준규, 김원석, 최창용, 장미경, 나재운
|
| 소속 |
순천대 |
| 키워드 |
N-carboxymethyl chitosan; LMWSC; ofloxacin
|
| E-Mail |
|
