Characterization of Polymers by Temperature Gradient Interaction Chromatography

Lee HC; Lee W; Chang T

Korea Polymer Journal, Vol.4, No.2, 160-165, October, 1996

Temperature gradient interaction chromatography for the characterization of molecular weight distribution of macromolecules is reported. The technique is a conventional reversed phase HPLC, but the column temperature is varied during the elution. A very fine and reproducible control of interaction between polymer chains and the stationary phase can be achieved by changing the column temperature. Under a suitable temperature programming, this method has been proven to provide a far better resolution to conventional size exclusion chromatography.

[References]

Giddings JC, Unified Separation Science, John Wiley, New York (1991)
Grockner G, Polymer Characterization by Liquid Chromatography, Elsevier, Amsterdam (1987)
Barth HG, Mays JW, Modern Methods of Polymer Characterization, Wiley and Sons, New York (1991)
Grockner G, HPLC of Copolymers and Chromatographic Cross-Fractionation, Springer-Verlag, Berlin (1992)
Amstrong DW, Bui KH, Anal. Chem., 54, 706 (1982)
Snyder LR, Stadalius MA, Quarry MA, Anal. Chem., 55, 1413A (1983)
Lochmuller CH, Jiang C, Elomaa M, J. Chromatogr. Sci., 3, 561 (1995)
Shalliker RA, Kavanagh PE, Rushell IM, Hawthorne DG, Chromatographia, 33, 427 (1992)
Northrop DM, Martire DE, Scott RPW, Anal. Chem., 64, 16 (1992)
Lochmuller CH, McGranaghan MB, Anal. Chem., 61, 2449 (1989)
Snyder LR, Kirkland JJ, Introduction to Modern Liquid Chromatography, 2nd ed. John Wiley and Sons, New York, pp. 715 (1979)
Melander WR, Chen BK, Horvath C, J. Chromatogr., 318, 1 (1985)
Lochmuller CH, Moebus MA, Liu Q, Jiang C, Elomaa M, J. Chromatogr. Sci., 34, 69 (1996)
Lee HC, Chang TY, Polymer, 37(25), 5747 (1996)
Tenikov MB, Nefedov PP, Nazareva MA, Frenkel SY, Visokomol. Soedin. Ser. A, 19, 657 (1977)
Hunkeler D, Macko T, Berek D, Am. Chem. Soc. Symp. Ser., 521, 90 (1993)
Pasch H, Polymer, 34, 4095 (1993)
Flory PJ, Principles of Polymer Chemistry, Cornell University Press, Ithaca (1953)

[Referenced By]

[1] Giddings JC, Unified Separation Science, John Wiley, New York (1991)

[2] Grockner G, Polymer Characterization by Liquid Chromatography, Elsevier, Amsterdam (1987)

[3] Barth HG, Mays JW, Modern Methods of Polymer Characterization, Wiley and Sons, New York (1991)

[4] Grockner G, HPLC of Copolymers and Chromatographic Cross-Fractionation, Springer-Verlag, Berlin (1992)

[5] Amstrong DW, Bui KH, Anal. Chem., 54, 706 (1982)

[6] Snyder LR, Stadalius MA, Quarry MA, Anal. Chem., 55, 1413A (1983)

[7] Lochmuller CH, Jiang C, Elomaa M, J. Chromatogr. Sci., 3, 561 (1995)

[8] Shalliker RA, Kavanagh PE, Rushell IM, Hawthorne DG, Chromatographia, 33, 427 (1992)

[9] Northrop DM, Martire DE, Scott RPW, Anal. Chem., 64, 16 (1992)

[10] Lochmuller CH, McGranaghan MB, Anal. Chem., 61, 2449 (1989)

[11] Snyder LR, Kirkland JJ, Introduction to Modern Liquid Chromatography, 2nd ed. John Wiley and Sons, New York, pp. 715 (1979)

[12] Melander WR, Chen BK, Horvath C, J. Chromatogr., 318, 1 (1985)

[13] Lochmuller CH, Moebus MA, Liu Q, Jiang C, Elomaa M, J. Chromatogr. Sci., 34, 69 (1996)

[14] Lee HC, Chang TY, Polymer, 37(25), 5747 (1996)

[15] Tenikov MB, Nefedov PP, Nazareva MA, Frenkel SY, Visokomol. Soedin. Ser. A, 19, 657 (1977)

[16] Hunkeler D, Macko T, Berek D, Am. Chem. Soc. Symp. Ser., 521, 90 (1993)

[17] Pasch H, Polymer, 34, 4095 (1993)

[18] Flory PJ, Principles of Polymer Chemistry, Cornell University Press, Ithaca (1953)