Chemiluminescent detection of tear glucose on paper microfluidic devices

Hyejung Jang; Hyeran Noh

Macromolecular Research, Vol.23, No.5, 493-495, May, 2015

DOI10.1007/s13233-015-3063-8 Export Citation

Chemiluminescent detection of tear glucose on paper microfluidic devices

Hyejung Jang, and Hyeran Noh^{1, †}

Department of Visual Optics, Seoul National University of Science and Technology, Seoul, 139-743, Korea
¹Department of Visual Optics, Convergence Institute of Biomedical Eng. & Biomaterials, Seoul National University of Science and Technology, Seoul, 139-743, Korea

E-mail:

Since the hydrogen pcroxide produced by the oxidation of glucosc is involved in a luminescent reaction, the chemiluminescent light intensity also decreased with time. It shows that quantitative analysis of chemiluminescence reaction on paper was possible. The light intensity shown on top of paper was sensitive enough to quantify the tear glucose at low concentration beblow 1mM.

[References]

Danaei G, et al., Lancet, 378, 378 (2011)
Ramachandram B, Lakowicz JR, Geddes CD, Anal. Chem., 76, 610 (2004)
Zhang J, Hodge W, Hutnick C, Wang X, J. Diabetes Sci. Technol., 5, 166 (2011)
Noh H, Phillips S, Anal. Chem., 82, 8071 (2010)
Martinez A, Phillips S, Whitesides GM, Proc. Natl. Acad. Sci. U.S.A., 105, 19606 (2008)
Delaney JL, Hogan CF, Tian J, Shen W, Anal. Chem., 83, 1300 (2011)

[Referenced By]

[1] Danaei G, et al., Lancet, 378, 378 (2011)

[2] Ramachandram B, Lakowicz JR, Geddes CD, Anal. Chem., 76, 610 (2004)

[3] Zhang J, Hodge W, Hutnick C, Wang X, J. Diabetes Sci. Technol., 5, 166 (2011)

[4] Noh H, Phillips S, Anal. Chem., 82, 8071 (2010)

[5] Martinez A, Phillips S, Whitesides GM, Proc. Natl. Acad. Sci. U.S.A., 105, 19606 (2008)

[6] Delaney JL, Hogan CF, Tian J, Shen W, Anal. Chem., 83, 1300 (2011)