화학공학소재연구정보센터
홈 로그인 로그아웃 연락처 사이트맵
Macromolecular Research, Vol.24, No.5, 478-481, May, 2016
DOI10.1007/s13233-016-4056-y  Export Citation
Generation Dependency of Stimuli-Responsive Dendron-Gated Mesoporous Silica Nanocontainers
Jeonghun Lee, Hyewon Kim, and Chulhee Kim†
  • Department of Polymer Science and Engineering, Inha University, Incheon, Korea
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On the surface of mesoporous silica nanoparticle (MSN), second and third generation polymidoainc (PAMAM) dcndrons were introduced as a gatckccper via disulfied bond, respectively (Si-SS-2G and Si-SS-3G). Due to the relationship between the size of dendron and MSN mesopore, the entrapped drug in Si-SS-2G was felease in the absence of any external stibuli, while that in Si-SS-3G was not. Upon addition of glutathione, the entrapped drug was released by removal of the dendron due to the reduction of disulfide bond.
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