In this paper, the disturbance decoupling problem (DDP) for a class of single-input-single-output (SISO) nonlinear systems with multiple delays in the input and the state is studied. A pioneering mathematical approach is introduced for this class of systems and is claimed to be the cornerstone of the problem. Necessary and sufficient conditions are given for the existence of a bicausal feedback that solves the DDP. Sufficient conditions for the existence of a solution within other classes of compensators are included as well.