Chemistry Letters, Vol.31, No.2, 158-159, 2002
Nucleophilic allylation-heterocyclization via bis-pi-allylpalladium complexes: Synthesis of five- and six-membered heterocycles
The reaction of the allylic halides 5-9 having an aldehyde or an imine moiety in the molecule with allyltributylstannane proceeded smoothly in the presence of Pd-2.dba(3)-CHCl3 (5 mol%) in DMF or THF, giving the corresponding heterocycles 10-14 in good to high yields. The Stille coupling product was not obtained under these reaction conditions.