스타형 폴리락티드의 가수분해 거동

김수현; 김영하

Polymer(Korea), Vol.20, No.3, 528-534, May, 1996

Export Citation

스타형 폴리락티드의 가수분해 거동

Hydrolysis Degradation of Star-shaped Poly-L-lactide

김수현, 김영하

초록

락티드를 stannous octoate촉매로서 개환중합하여 선형 폴리락티드를 중합하였고, 펜타에 리트리톨을 첨가하여 스타형 폴리락티드를 제조하였다. 스타형 및 선형 폴리락티드의 가수분해 거동을 분석한 결과, 스타형 구조는 chain arm의 수가 많으므로 초기에는 직선형 수조보다 분자량의 감소가 지연되었으나 어느 시점 이후에는 오히려 가수분해가 가속되는 현상이 관찰되었다.

The poly-L-lactide was synthesized by ring-opening polymerization of L-lactide with stannous octoate. Star-shaped poly-L-lactide was also prepared by the addition of pentaerythritol. The hydrolysis degradation behavior of linear and star-shaped poly-L-lactides was investigated. The star polymer showed a lower decrease rate of molecular weight than the linear one in the initial stage since it has multi chain arms.

Keywords:polyactide;hydrolysis;star-shaped

[References]

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[1] Wise DL, "Biopolymeric Controlled Release System," D.L. Wise, Ed., Vol. 1, Chap. 8, CRC Press, Boca Raton (1985)

[2] Vert M, Christel P, Chabot F, Leray J, "Macromolecular Biomaterials," G.W. Hastings and P. Ducheyne, Eds., Chap. 6, CRC Press, Boca Raton (1984)

[3] Lenz RW, "Advances in Polymer Science," N.A. Peppas and R.S. Langer, Eds., Vol. 107, p. 1-41, Springer-Verlag, Berlin (1993)

[4] Tunc DC, Polym. Prepr., 27(1), 431 (1986)

[5] Grijpma DW, Nijenhuis AJ, VanWijk PGT, Pennings JA, Polym. Bull., 29, 571 (1992)

[6] Gruver JT, Kraus G, J. Polym. Sci. A: Polym. Chem., 3, 105 (1965)

[7] Kim SH, Han YK, Kim YH, Hong SI, Makromol. Chem., 193, 1623 (1992)

[8] Kim SH, Han YK, Ahn KD, Kim YH, Chang T, Makromol. Chem., 194, 3229 (1993)

[9] Kricheldorf HR, Kreisersaunders I, Boettcher C, Polymer, 36(6), 1253 (1995)

[10] Makino K, Ohshima H, Kondo T, J. Microencaps., 3(3), 203 (1986)

[11] Williams DF, J. Mater. Sci., 17, 33 (1982)

[12] Leenslag JW, Pennings AJ, Boss RRm, Rozema FR, Boering G, Biomaterials, 8, 311 (1987)

[13] Kronenthal RL, "Polymer Science and Technology," A.R. Irvine, Ed., Vol. 8, p. 114, Plenum Press (1974)

[14] Fischer EW, Sterzel HJ, Wegner G, Kolloid-Z. Z. Polym., 251, 980 (1973)

[15] Li SM, Vert M, Macromolecules, 27(11), 3107 (1994)