Nelumbo nucifera extracts as whitening and anti-wrinkle cosmetic agent

Tagon Kim; Hee Jin Kim; Sung Ki Cho; Whan Yul Kang; Hyun Baek; Hye Young Jeon; Boyoung Kim; Donguk Kim

Korean Journal of Chemical Engineering, Vol.28, No.2, 424-427, February, 2011

DOI10.1007/s11814-010-0357-6 Export Citation

Nelumbo nucifera extracts as whitening and anti-wrinkle cosmetic agent

Tagon Kim, Hee Jin Kim, Sung Ki Cho, Whan Yul Kang¹, Hyun Baek¹, Hye Young Jeon¹, Boyoung Kim¹, and Donguk Kim^†

Department of Pharmaceutical Engineering, Inje University, Gimhae, Gyeongnam 621-749, Korea
¹Amaranth Cosmetics, 1534-2, Songjung-dong, Gangseo-gu, Busan 618-817, Korea

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Water extract from Nelumbo nucifera was tested for possible functional cosmetic agent. Whitening effect was measured by tyrosinase inhibition assay and DOPA-oxidase inhibition assay, and anti-wrinkle effect was checked by elastase inhibition assay. DOPA-oxidase inhibition effect (whitening effect) of Nelumbo nucifera’s leaf, seed and flower extract was 59%, 57% and 50%, respectively. Nelumbo nucifera’s leaf, seed and flower extract showed 56%, 49%, and 54% elastase inhibition (anti-wrinkle effect) at 200 μg/ml, while adenosine indicated 26% inhibition. Water cream including Nelumbo nucifera’s root, leaf, flower, stem extract did not cause significant skin irritation. Water cream including 4% Nelumbo nucifera extract was stable for 30 days under various temperature conditions. From the study, Nelumbo nucifera’s leaf, flower and seed extracts showed strong possibility for whitening and anti-wrinkle functional cosmetic agent.

Keywords:Nelumbo nucifera;Cosmetics;Whitening;Anti-wrinkle;Safety

[References]

Zastrow L, Groth N, Klein F, Kockott D, Lademann J, Ferrero L, IFSCC., 11, 207 (2008)
Rudolph T, Buhle P, Beck J, Plucker F, Reiffen KA, Buchlolz H, IFSCC., 9, 211 (2006)
Ha BC, Cosmeceuticals, Shin Kwang Publishing, Seoul (2005)
KDA Textbook Editiong Board, Dermatology, 5th Ed., Ryo Mook Gak, Seoul (2008)
http://www.khidi.or.kr (2009)
Korea Food and Drug Administration, http://www.kfda.go.kr/index.html (2009)
Elsner P, Mailbach HI, Cosmeceuticals and active cosmetics, 2nd Ed., Taylor & Francis, New York (2005)
Kim JY, Yang HJ, Lee KH, Jeon SM, Ahn YJ, Won BR, Park SN, J. Soc. Cosmet. Scientists Korea., 33, 165 (2007)
Vielhaber G, Schmaus G, Jacobs K, Franke H, Lange S, Hermann M, Joppe H, Koch O, IFSCC., 9, 227 (2006)
Hong ES, Nguyen DTM, Nguyen DH, Kim EK, Korean J. Chem. Eng., 25(6), 1463 (2008)
Pillai R, Redmond M, Roding J, IFSCC., 8, 17 (2005)
Park JC, Functional food, Hyoil Books, Seoul (2007)
Fujita Y, Hehara I, Morimoto Y, Nakashima M, Hatano T, Okuda T, Yakugaku Zasshi., 108, 129 (1988)
Kim JY, Yang HJ, Lee KH, Jeon SM, Ahn YJ, Won BR, Park SN, J Soc. Cosmet. Scientists Korea., 33, 165 (2007)
Erdemogu N, Sener B, ide S, J. Mol. Struct., 559, 227 (2001)
Luo X, Chen B, Yao SL, Anal. Chim. Acta., 538, 129 (2005)
Bhattachary SK, Bose R, Tripathi VJ, Ray AB, Dasgupta B, Psychopharmacology., 59, 29 (1978)

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[1] Zastrow L, Groth N, Klein F, Kockott D, Lademann J, Ferrero L, IFSCC., 11, 207 (2008)

[2] Rudolph T, Buhle P, Beck J, Plucker F, Reiffen KA, Buchlolz H, IFSCC., 9, 211 (2006)

[3] Ha BC, Cosmeceuticals, Shin Kwang Publishing, Seoul (2005)

[4] KDA Textbook Editiong Board, Dermatology, 5th Ed., Ryo Mook Gak, Seoul (2008)

[5] http://www.khidi.or.kr (2009)

[6] Korea Food and Drug Administration, http://www.kfda.go.kr/index.html (2009)

[7] Elsner P, Mailbach HI, Cosmeceuticals and active cosmetics, 2nd Ed., Taylor & Francis, New York (2005)

[8] Kim JY, Yang HJ, Lee KH, Jeon SM, Ahn YJ, Won BR, Park SN, J. Soc. Cosmet. Scientists Korea., 33, 165 (2007)

[9] Vielhaber G, Schmaus G, Jacobs K, Franke H, Lange S, Hermann M, Joppe H, Koch O, IFSCC., 9, 227 (2006)

[10] Hong ES, Nguyen DTM, Nguyen DH, Kim EK, Korean J. Chem. Eng., 25(6), 1463 (2008)

[11] Pillai R, Redmond M, Roding J, IFSCC., 8, 17 (2005)

[12] Park JC, Functional food, Hyoil Books, Seoul (2007)

[13] Fujita Y, Hehara I, Morimoto Y, Nakashima M, Hatano T, Okuda T, Yakugaku Zasshi., 108, 129 (1988)

[14] Kim JY, Yang HJ, Lee KH, Jeon SM, Ahn YJ, Won BR, Park SN, J Soc. Cosmet. Scientists Korea., 33, 165 (2007)

[15] Erdemogu N, Sener B, ide S, J. Mol. Struct., 559, 227 (2001)

[16] Luo X, Chen B, Yao SL, Anal. Chim. Acta., 538, 129 (2005)

[17] Bhattachary SK, Bose R, Tripathi VJ, Ray AB, Dasgupta B, Psychopharmacology., 59, 29 (1978)